"Girls Just Want to Have Sums"

(Click promo card to enlarge)

The April 30, 2006 episode of The Simpsons:

Springfield is in an uproar after Principal Skinner makes a sexist comment at the end of an Itchy and Scratchy musical. Principal Skinner is replaced by Melanie Upfoot, a women's educational expert, who decides to divide the school in two: one for boys, and one for girls. Studious Lisa soon becomes frustrated when she isn't learning anything from girls' school.

When the Principal refuses to allow her to take math at the boys' school, Lisa decides to dress up as a boy. While Bart teaches her the ropes of boyhood, Lisa wins the math award at the Student Achievement Awards and learns what it's really like to be a part of the boys' club.

Frances McDormand guest-stars as Principal Melanie Upfoot.